WebA functional nuclear imaging study using SPECT 99mTc-TRODAT-1, a specific imaging agent for dopamine transporter (DAT), reported reduced DAT availability during a 6-month follow-up period was associated with impaired cognitive performance, which indicates a crucial role for DAT in the recovery of executive function following CO poisoning [ 29 ]. WebMar 9, 2024 · SPECT Ioflupane123I (DaTscan), 99mTc (TRODAT) and Ioflupane with Myocardial Scintigraphy 123I (MIBG) for Diagnosis of Parkinson’s Disease Clinical …
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Webevaluate the clinical usage of 99mTc-TRODAT-1 SPECT imaging in the diagnosis of major depressive disorder and PD. METHOD Participants A total of 17 PD patients, 13 MDD patients, and 10 healthy-comparison subjects from our hospital were en-rolled in this study. Characteristics of these patients and healthy subjects were summarized in Table 1. No ... WebAug 23, 2024 · In conclusion, in our study, SPECT-TRODAT-1 was important to corroborate a diagnostic hypothesis, mainly to differentiate some types of Parkinsonism. This study … community works west sf
Higher striatal dopamine transporter density in PTSD: an in vivo SPECT …
WebJan 3, 2012 · SPECT is an aid that can help diagnosing the disease earlier. 2. Imaging Agent of SPECT for PD The ligands used for SPECT belong to a group of compounds derived from cocaine that bind to the dopamine transporter and include IPT, TRODAT-1, and FP-CIT tagged with either iodine-123 (T1/2 = 13.2 h) or technetium-99 m (T1/2 = 6 h) radioisotopes. WebAt present, 99m Tc-TRODAT-1 single photon emission computed tomography (SPECT) is the most widely applied approach in Taiwan. 99m Tc-TRODAT-1 tracers mark the dopamine transporter (DAT) in the neuronal presynaptic membrane by binding to the relevant receptors after intravenous injection. WebMar 1, 2004 · SPECT dopamine transporter Parkinson’s disease The current diagnosis of idiopathic Parkinson’s disease (PD) is substantially based on the clinical symptoms—including resting tremor, rigidity, bradykinesia, and postural instability—as well as a favorable response to levodopa therapy. eatable marshmallow confection