Ly49h 3d10
WebThe 3D10 monoclonal antibody specifically binds to mouse Lymphocyte antigen 49H (Ly-49H; also known as Klra8 or Killer cell lectin-like receptor 8). The 3D10 antibody does not crossreact with related molecules such as Ly-49A, C, D or G2. Ly-49H is a type II transmembrane protein and a member of the Ly-49 C-type lectin multigene family of … Web15 nov. 2004 · Ly49H(+) NK cells play a critical role in innate antiviral immune responses to murine CMV (MCMV). Ly49H(b6) recognition of MCMV-encoded m157 on infected cells activates natural killing required for host resistance. We show that mAb 3D10 (anti-Ly49H) recognizes comparable subsets of NK cells from New …
Ly49h 3d10
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WebPE anti-mouse Ly49H [3D10]; Isotype: Mouse IgG1, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg IgGy Antibody Selector – Quickly search hundreds of thousands of antibodies … WebFITC anti-mouse Ly49H Antibody - Ly49H, also known as Cmv1 and Klra8, is a 28.3 kD protein. It is expressed on NK cells (but not on NKT cells) from C57BL/6 mice (but not …
Web30 mar. 2009 · The blocking anti-Ly49H mAb (clone 3D10) or an isotype-matched control mAb was added to the indicated cultures at 5 µg/ml. 6 h later, supernatants were harvested and assayed for 51 Cr release. Spontaneous lysis was determined by incubating target cells without effectors. Maximum lysis was determined by incubating target cells in 1% Triton X ... Web1 iun. 2024 · (A and B) Percentage of transferred Ly49H + NK cells that are WT (CD45.1) versus Ncr1 Cre × Ldha flox/flox (CD45.2) in the blood of Ly49H-deficient hosts during the course of MCMV infection (A), and in the spleen and liver harvested at >30 days PI (B). (C) Ly49H expression level of Ly49H + WT and LDHA-deficient NK cells at day 7 PI.
Web4 aug. 2015 · WT splenic Ly49H + NK cells were transferred into Ly49H-deficient mice and infected with MCMV. Shown are representative histograms and quantification of mean fluorescence intensity (MFI) for tetramethylrhodamine ethyl ester (TMRE) staining (A), MitoSox Red staining (B), or MitoTracker Green staining (C) in transferred NK cells from … WebRequest Bulk Quote. Description. Ly49H, also known as Cmv1 and Klra8, is a 28.3 kD protein. It is expressed on NK cells (but not on NKT cells) from C57BL/6 mice (but not …
WebRequest Bulk Quote. Description. Ly49H, also known as Cmv1 and Klra8, is a 28.3 kD protein. It is expressed on NK cells (but not on NKT cells) from C57BL/6 mice (but not …
Web18 aug. 2015 · NK Cells Undergo Dynamic Changes in Mitochondrial Quality in Response to Viral Infection In Vivo. WT splenic Ly49H + NK cells were transferred into Ly49H-deficient mice and infected with MCMV. Shown are representative histograms and quantification of mean fluorescence intensity (MFI) for tetramethylrhodamine ethyl ester (TMRE) staining … liberty wines timbermill wayWeb8 aug. 2016 · However, no differences in the proportion of Ly49C, Ly49D, and Ly49H expressing NK cells was observed between SLP-76 KO BM and WT BM-derived NK cells . Thus, although a subset of Ly49 receptors (Ly49A, G2, and I) was regulated in an NK cell-intrinsic manner, Ly49C, Ly49D, and Ly49H were controlled by a SLP-76-dependent, NK … liberty wire \u0026 cable incWeb22 sept. 2024 · To investigate the role of T and B cells in adaptive NK cell responses against MCMV infection, we compared Ly49H + NK cell expansion in wild-type (WT) mice versus Rag2 −/− mice, which lack adaptive lymphocytes. Whereas WT mice exhibited a robust NK cell response, peaking ∼7 days post-infection (PI), Rag2 −/− mice showed a diminished … liberty wireless usviWeb5 iun. 2008 · The small but significant percentage of 3D10-specific NKT cells suggests that either Ly49H is expressed on NKT cells or, more likely, that a closely related inhibitory … mchughes hireWebThe Ly49H + NK cell counts were similar in the spleen and liver of Adrb2 −/− and control Adrb2 +/+ littermates at 44 h after MCMV infection . Moreover, the higher frequency of IFN-γ–producing NK cells in the liver of Adrb2 −/− mice at 44 h pi involved both the Ly49H-positive and -negative subsets ( Fig. 3 E ). liberty wire cableWebProduct Specific Information. Description: The monoclonal antibody 3D10 recognizes Ly49H, a member of the C-type lectin Ly-49 multigene family … liberty wines granville islandWebThe 3D10 monoclonal antibody specifically binds to mouse Lymphocyte antigen 49H (Ly-49H; also known as Klra8 or Killer cell lectin-like receptor 8). The 3D10 antibody does … liberty winnipeg